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Asking Price: Not Disclosed

Clinical Stage Oncology Co. for Early Cancer Detec

Chicago, IL
Cook County

The Company is a clinical-stage oncology company with a platform that combines biospectral impedance and AI/ML for point-of-care cancer detection. The lead product delivers rapid, in-procedure assessment of surgical margins—identifying the presence and location of cancer within minutes. Initial commercialization targets skin cancer, where the lead product can shorten procedures, spare healthy tissue, improve surgeon economics, and enhance outcomes. The Company has also built a compelling breast cancer dataset and plans to deploy the lead product to help dramatically reduce the ~20–25% re-surgery (re-excision) rate in partial mastectomies; the breast program is in line for non-dilutive CPRIT support.The Company has a collaboration with PHC Holdings (formerly Panasonic Healthcare; TSE:6529) to commercialize the lead product. The company anticipates FDA clearance in 2026 and profitability in 2028.Beyond skin and breast, the Company has generated promising data in lung, pancreatic, esophageal, and colon tissue. Follow-on products include a rapid biopsy-assessment device and a needle-based device leveraging the same platform.Use of Proceeds: This round will fund FDA clearance activities and the initial commercial launch of the lead product.NDA is required to receive comprehensive Confidential Information Memorandum (CIM) crafted by ProNova Partners.

Cash Flow $1,091
Revenue $9,498
$ Owner Financing Available

Asking Price: $4,900,000

Five Locations/Towns Service Suite CRE Portfolio

Hoffman Estates, IL
Cook County

DESCRIPTION:OVERVIEWFor sale is a multi-property commercial real estate portfolio comprising retail-facing service suites (“professional suite” units) for independent B2C service providers. The sale includes all owned building parcels, plus the leasing/tenant-management operation, which has maintained nearly 20 years of operating history and 96% /- average occupancy (per seller).This opportunity is best underwritten as a stabilized, diversified-tenant CRE investment with value-add rent upside (not a traditional owner-operator business).WHAT YOU’RE BUYING- Multiple owned commercial properties across several nearby towns (Chicagoland / Cook & Multi-County area)- A proven suite-based leasing model with dozens of small tenants per location- A low-touch management operation (can be self-managed or outsourced)PORTFOLIO HIGHLIGHTS- 96% /- occupancy across the portfolio (per seller)- Diversified tenant base (many small service professionals vs. single-tenant risk)- Modern, clean, secure buildings in well-maintained areas- Units designed for tenant customization with upscale interior finishes / aesthetic flexibility- Long-standing concept with consistent leasing demand for almost 2 decadesFINANCIAL SNAPSHOT (AS PRESENTED)- Asking Price: $4,900,000- Annual Revenue: $971,102- SDE: $638,644 - Real Estate Value Component: 5 Commerical Condos at 5 different locations/towns included- FF&E: $500,000 | Inventory: $10,000VALUE-ADD / GROWTH OPPORTUNITIESSeller indicates many units are 20% or more below market rent. Upside levers include:- Phased rent increases at renewal (protect occupancy while resetting rates)- Immediate mark-to-market on new leases- Standardized pricing/rate cards across locations- Modest, targeted improvements that support higher rents OPERATIONS & MANAGEMENT- Current ownership runs this as a low-touch, efficient leasing property oversight model- New owner can manage directly or hire a property management company (commonly feasible due to the model’s simplicity)BUYER FITIdeal for:- Value-add CRE investors seeking stabilized occupancy rent reset upside- Family offices / HNW buyers wanting durable cashflow backed by owned real estate- 1031 exchange buyers looking for diversified, income-producing property- Operators already in service suites / professional suites who can systematize leasing and pricingNot ideal for:- SBA buyers / owner-occupied financing structuresFINANCING NOTE (IMPORTANT)This is not typically SBA-eligible due to the non-owner-occupied nature (many tenant occupants). Expect commercial real estate lending terms, often requiring ~20–30% down (varies by lender/structure). Some lenders may require a compensating balance in an account in addition to the equity injection.REASON FOR SALEOwner is selling to semi-retire, pursue other interests, and relocate full-time.

Cash Flow $638,644
Revenue $971,102

Asking Price: $260,000

PRICE REDUCED! Established Sign and Print Fran.

Not Disclosed, IL
Cook County

PRICE REDUCED! Established Sign and Print FranchiseNow $260,000 (Reduced from $295,000) – Motivated Seller!An exceptional opportunity to acquire a long‑standing sign and print franchise with 24 years of operating history, a strong reputation for quality, and a diverse commercial customer base. The current owner has operated the business for nearly five years and is offering the company at a reduced price to facilitate a timely transition. The business generates $111,699 in Seller’s Discretionary Earnings (SDE) and operates efficiently with three employees (two full‑time, one part‑time). This structure provides an ideal platform for an owner‑operator, sales‑driven buyer, or entrepreneur seeking a proven, scalable business model. Comprehensive Sign & Print Capabilities The company delivers a full suite of visual marketing solutions, including custom signage, digital printing, banners, vehicle wraps and graphics, trade show displays, branded materials, and other high‑demand commercial products. Its broad customer mix reduces dependency on any single client and supports stable, recurring revenue.An Attractive Acquisition OpportunityWith more than two decades in business, this franchise offers the advantages of an established operation — brand recognition, proven systems, trained staff, and a loyal customer base — without the challenges of starting from scratch.A new owner could potentially increase revenue and profitability through:More aggressive local sales and business developmentExpanding relationships with existing commercial customersIncreasing recurring orders and repeat businessDigital marketing and social media initiativesDeveloping new corporate and small-business accountsExpanding higher-margin products and servicesBuilding strategic relationships with contractors, real estate professionals, event companies, and other local businessesKey Highlights20 years in businessCurrent owner for 4 yearsSDE: $111,6993 employeesEstablished customer baseRecognized franchise brandComprehensive sign and printing capabilitiesStrong reputation for quality and customer serviceAsking price has been reduced from $295,000 to $260,000Attractive opportunity for an owner-operator or sales-driven buyer

Cash Flow $111,699
Revenue $378,597

Asking Price: $100,000

Semi-Absentee Tutoring Franchise in South Suburbs

Not Disclosed, IL
Cook County

This is an exceptional opportunity to own a well-established supplemental education business that has been serving its local community for over 15 years. As part of a nationally recognized franchise network with over 45 years of experience in K–12 education, this center is known for delivering high-impact, personalized academic support.The business offers a full range of academic services for grades K–12, including reading, math, writing, study skills, homework support, and test preparation. Programs are delivered through a combination of proven curriculum, engaging technology, and certified educators, creating individualized learning experiences that drive real results for students.Strategically located in a well-maintained retail center with excellent visibility on a high-traffic street, the facility is easily accessible and surrounded by a solid middle-class customer base. The location is professionally outfitted and provides a welcoming, productive environment for students and families.For this potential buyer who chooses to owner/operate the business, there's significant upside: Seller’s Discretionary Earnings (SDE) can exceed $100,000 annually, based on current performance and cost structure. For qualified buyers, seller financing available.Business Highlights:15 years of success in a growing, education-focused marketFull range of K–12 tutoring and test prep servicesCertified instructors and personalized learning programsPrime location in a high-traffic, well-kept retail centerOver $100K in SDE for an owner/operatorTurnkey operation with ongoing franchisor support and trainingSeller financing available​Whether you're looking for a semi-passive investment or a hands-on role in a meaningful, purpose-driven business, this opportunity offers strong returns, community impact, and room to grow.Serious inquiries only. NDA and conversation with business broker required before CIM is released.

Cash Flow $45,000
Revenue $368,310

Asking Price: $400,000

Established Primary & Immediate Care Clinic

Not Disclosed, IL
Cook County

Opportunity to acquire a physician-owned medical practice providing comprehensive primary and immediate care services to patients of all ages. Founded in 2018 by a board-certified family medicine doctor with over 15 years of clinical experience, the clinic has built a strong local reputation for compassionate care, clinical excellence, and operational efficiency. The owning physician will be leaving the practice after an agreed upon transition period. The practice is best suited for a new owning physician.The practice serves a wide range of medical needs—from wellness visits and chronic disease management to immediate care, lab testing, and minor in-office procedures such as biopsies, cryotherapy, and laceration repair. Its diverse service mix generates consistent revenue, with recent annual sales of $380,029 and Seller’s Discretionary Earnings (SDE) of $162,071, representing a healthy 43% profit margin. The clinic is in-network with major insurers including BCBS, UnitedHealthcare, and Cigna, and operates with a lean, efficient team. Also accepts Medicare and Medicaid.Located in a modern medical office building in Hoffman Estates, IL, the facility includes three exam rooms, 2 office spaces for doctors, and a spacious waiting area in the rented office space. The purchase will also include diagnostic equipment currently at the facility. The business is ideal for a physician-owner, group practice, or strategic healthcare operator seeking a turnkey opportunity in a high-demand suburban market. With a loyal patient base, high online ratings, and growth potential through extended hours or additional services, this is a rare chance to acquire a well-run, reputable clinic with deep community ties.

Cash Flow $162,071
Revenue $380,029

Asking Price: $6,000,000

Premier OB/GYN & Med Spa Practice – Chicago Suburb

Hoffman Estates, IL
Cook County

Established in 2005, this award-winning OB/GYN and Med Spa practice offers a rare opportunity to acquire a highly regarded women’s health business with a 20-year track record in the northwest suburbs of Chicago. The practice provides comprehensive OB/GYN care across all stages of a woman’s life — including high-risk pregnancy, infertility treatment, menopause management, minimally invasive robotic-assisted surgeries, and more — paired with a growing med spa division offering Botox, laser hair removal, weight loss, skin tightening, a clinic branded skincare product line and membership program, and other aesthetic services.The clinic is supported by a tenured team of 15, including the founding OB/GYN, nurse practitioner, certified nurse midwives, licensed aestheticians, and full administrative and clinical support staff. It holds hospital affiliations with AMITA Health St. Alexius, Alexian Brothers, and Associated Surgical Center, and is strategically located to draw patients from Hoffman Estates, Schaumburg, Arlington Heights, Palatine, and beyond. The practice maintains a 94% patient satisfaction rate, with patients consistently highlighting the team’s compassionate and personalized approach.Over the past six years, the business has averaged $3.3M in revenue and $1.3M in adjusted SDE (~38%) reflecting strong and consistent performance. The founding physician is preparing to retire, presenting a unique succession opportunity for a buyer to step in and capitalize on the clinic’s strong brand, established infrastructure, and expanding high-margin services. Ideal for private equity or strategic healthcare buyers seeking a scalable platform or bolt-on in women’s health, fertility, and aesthetics.

Cash Flow $1,285,910
Revenue $3,341,954

Asking Price: $175,000

20K Price Drop! Health and Wellness Body Spa

Not Disclosed, IL
Cook County

20K Price Drop! Health and Wellness Body Spa, Fire Sale!A premier health and wellness body spa specializing in post-cancer care and noninvasive body contouring is now available for acquisition. Established 6 years ago by a registered nurse and certified manual lymphatic therapist, this business has become a trusted destination for clients, particularly those in remission from cancer requiring specialized treatments such as manual lymphatic drainage and sauna therapy.Business Highlights:• Expert Care: The current owner is a certified manual lymphatic therapist and registered nurse, ensuring the highest standard of care.• Specialized Services: The spa offers manual lymphatic drainage and sauna therapy, crucial for post-cancer healing.• Financial Accessibility: Accepts FSA Flex Spending and HSA Health Spending Account, CareCredit, and Cherry Financing. The business has also applied for health insurance approval with BCBS and United Healthcare.• Media Recognition: Business was selected to film a special with BeSpire TV about breast cancer, featuring a 30-minute to 1-hour documentary.• Strategic Partnerships: Collaborates with Advocate and U of I, serving as a referral destination for their patients in remission from cancer.• Certifications in Progress: The business is in the process of being certified as a Women’s Business Enterprise (WBE) and Women-Owned Small Business (WOSB).• Prestigious Alumni: The owner is a graduate of the Goldman Sachs 10,000 Small Businesses Chicago program.• Community Involvement: Active members of the 95th Street Business Association, Beverly Area Planning Association, Chicagoland Chamber of Commerce, and National Association of Women Business Owners (NAWBO).Ideal Buyer Profile:The ideal buyer is a healthcare professional, such as a nurse, physician, licensed massage therapist, or physical therapist, who can adapt quickly and has a strong, eager-to-learn personality. This opportunity is perfect for someone who doesn't just follow scripts but genuinely understands the intricacies of the treatments offered. The current owner is committed to providing thorough training to ensure a smooth transition.This thriving health and wellness body spa is more than a business; it’s a community cornerstone that enhances the confidence and well-being of its clients. Don’t miss this unique opportunity to acquire a well-established, reputable business in a growing industry.Contact us today to learn more about this exciting opportunity!

Cash Flow $84,399
Revenue $257,555

Asking Price: $575,000

Profitable $1M+ Underground Irrigation Union Shop

Not Disclosed, IL
Cook County

Calling all Union Plumbers in the Chicago area seeking to enhance their footprint in the irrigation space! This consistently profitable underground irrigation company has served the Northern Illinois market for more than 100 years!, Specializing in commercial systems for businesses, this business boasts a robust client base, consistent revenue growth and a sterling reputation. Owner is willing to stay on to train and transition business to the next owner. Seize the opportunity to own a well-established and highly reputable irrigation business with a strong foothold in the market. Key Features include: established clientele, comprehensive services, experienced team, prime Location (easy on and off highway) and modern equipment and vehicles. Assets Included: Vehicles, machinery, tools, and inventory. Expansion opportunities exist with additional service areas, adding new services such as water management consulting, and targeting large-scale commercial contracts. Owner is seeking to retire and is motivated to find the right buyer who can continue the legacy and drive the business forward. Call us today to learn more! PLEASE NOTE: A PLUMBER'S LICENSE IS NEEDED TO RUN THIS BUSINESS! There are specific ways to keep the current plumbing license on file, but the strategic buyer for this business has access to a licensed plumber who will join the team after purchase

Cash Flow $202,000
Revenue $1,380,000

Asking Price: $735,000

Security Firm with Government Contracts & Long-Term Clients

Not Disclosed, IL
Cook County

Trusted Security Firm w/Government Contracts & Long-Term ClientsBusiness OverviewAn exceptional opportunity to acquire a well-established security company in Chicago, IL, founded in 1979 by a retired Chicago Police Lieutenant. This family-owned business, now in its second generation of leadership, has built a stellar reputation for providing top-notch security services for over four decades.Key HighlightsCertifications:- DBE Certified: By the Illinois Universal Certification Program (IL UCP) and the City of Chicago.- Live-Scan Fingerprint Services: Certified by the Illinois State Police.- Security Training School: Certified by the Illinois Department of Financial & Professional Regulations (IDFPR) to train both armed and unarmed security personnel.Clientele: The company boasts a loyal client base with many clients utilizing their services for over 20 years. They are the trusted security provider for high-profile corporate clients with sensitive requirements and numerous public venues that demand high levels of customer service and security due to their high threat target profiles.Services:- Comprehensive security solutions for businesses and public venues.- Live-Scan fingerprint services.- Training programs for security personnel, including both armed and unarmed security training.Why This Business?- Longevity and Trust: Established credibility with long-term client relationships.- Diverse Service Offering: Broad range of services catering to high-profile and sensitive security needs.- Growth Potential: Strong foundation for expansion in the security industry with established federal, state, and local certifications.This is a unique opportunity to acquire a well-respected and certified security company with a proven track record and a bright future. Perfect for an existing security firm looking to expand or an entrepreneur ready to step into a thriving business with a solid foundation.

Cash Flow $107,575
Revenue $8,219,165
$ Owner Financing Available

Asking Price: $599,999

Renowned African Fashion Store for Sale

Chicago, IL
Cook County

For over 15 years, this Chicago-based African fashion boutique has been a beloved destination for vibrant, authentic African clothing, shoes, jewelry, bags, arts and crafts, and waist beads. The store specializes in offering a curated selection of high-quality items sourced from diverse countries, including Ghana, Dubai, Nigeria, Italy, and beyond, creating a unique fusion of global styles and traditional African craftsmanship.The business is known for its rich cultural offerings and has established strong relationships with international dealers, designers, and wholesalers, ensuring the authenticity and exclusivity of its inventory. Customers have long appreciated the boutique’s commitment to providing items that celebrate African heritage while embracing modern trends.As the current owner prepares to transition the business, they are committed to staying on as a consultant to help the new owner seamlessly continue the boutique’s legacy. This support will include guidance on importing the specialty items and transferring well-established relationships with international suppliers. The seller’s mentorship will ensure the new owner not only preserves but also enhances these crucial connections, enabling a smooth and successful transition.This is an excellent opportunity for a buyer passionate about fashion, culture, and global business, with the added benefit of ongoing support from a seasoned professional in the industry.

Cash Flow Not Disclosed
Revenue Not Disclosed

Asking Price: $150,000

A handyman franchised business in a thriving area!

Not Disclosed, IL
Cook County

This service based business is a lucrative opportunity to own a well established business that is generating revenue. The systems are all in place for the next owner ! With low overhead and great profit margins that are very attainable, this one fits the bill for an owner operator or just an owner to facilitate daily operations . With the ever growing and continuous need for home repairs and maintenance , growth and scalability is inevitable. The listing price does not include the 4 service vans that run this business. Those franchised logo wrapped vehicles can be purchased for an additional $100k. Reach out to me for more information , before this one disappears from the market.The business was started in May of 2021 with one service technician. Within in 60 days of starting, two othertechnicians were hired because of the workload. The company is structured with three service technicians andone customer service rep. The owner works with the daily operations from an office.Potential GrowthBy following the proven Franchise systems that are in place along with providing great service, this business isvery scalableCompetitive OverviewThe handyman franchise industry in the United States is experiencing notable growth and transformation in 2025,driven by increased consumer demand, technological advancements, and evolving market dynamics.Market Size and Growthn Industry Value: The U.S. handyman services market is projected to reach $273.6 billion in 2024, witha modest growth rate of 0.9% for the year.High Household Demand: Approximately 80% of U.S. households require handyman servicesat least once annually, predominantly for residential needs.Outlook:The handyman franchise industry is poised for continued growth, driven by sustained demand,technological adv

Cash Flow $73,979
Revenue $495,522
$ Owner Financing Available

Asking Price: Not Disclosed

IllinoisCraft Grower Cannabis License

Not Disclosed, IL
Cook County

Offered is a fully awarded and transferable Adult-Use Craft Grower License in the State of Illinois. This license is one of the limited number issued under the Illinois Department of Agriculture’s cannabis program and presents a prime opportunity to enter the $2 billion Illinois cannabis industry without waiting on application cycles or the state lottery. The license provides the opportunity to grow/cultivate, process/manufacture , infuse, extract & distribute. This is an asset-only sale. No business, facility, or real estate is included. The buyer will need to establish a compliant location, facility, and operational plan post-acquisition. The license is eligible for expansion from 5,000 sq ft of flowering canopy up to 14,000 sq ft with state approval.Key HighlightsLicense Type: Adult-Use Craft Grower License (Illinois)Status: Fully awarded by the State of IllinoisTransferability: Permitted with State approval (buyer must qualify)Includes: License only – no operations, equipment, or real estateWhy This is a Great BuyScarcity Value: Illinois has tightly limited the number of licenses. Few are available on the open market.Fast Market Entry: Skip the years-long wait and uncertainty of license applications and approval.Strong Profit Potential: Cultivation operations, once built, can generate high 6-figure to multi-million dollar revenues annually depending on scale, product type, and distribution.High Demand: Illinois cannabis sales topped $2 billion in 2024, and the demand continues to rise for high-quality, locally grown cannabis products.What You’ll Need to Launch OperationsSecuring compliant real estate (zoned for cannabis cultivation)Facility design and build-out ($500K–$5M estimated depending on scale)Staff hiring and trainingSeed-to-sale compliance software and SOPsSecurity system and compliance plan per state regulationsIdeal BuyerThis opportunity is perfect for:MSOs (Multi-State Operators) looking to expand into IllinoisInvestors seeking entry into a highly regulated, high-margin industryDispensary owners looking to vertically integrateSocial equity applicants or groups with facility access and capitalFacilities and Assets IncludedNone. This listing is for the license only.Support & TrainingSeller will provide support during the transition period and assist with steps related to transferring the license in compliance with Illinois Department of Agriculture requirements. Willing to share Location Leads , industry resources.Reason for SellingStrategic business pivot. Seller is not launching a facility and is offering the license to an investor or operator better positioned to enter the market.

Cash Flow Not Disclosed
Revenue Not Disclosed

Asking Price: $1,150,000

Profitable & Independent Insurance Agency

Not Disclosed, IL
Cook County

Wildly successful independent insurance agency for sale with minimum 35% year over year growth since 2020 focusing on mainly personal auto insurance AND a separate revenue stream (i.e. car registration that makes up 46% of revenue) located next to a DMV. We repeat that almost 50% of the revenue of this business comes from car registration sales. For those looking for only a book of insurance business to transfer without this additional revenue stream being taken into consideration, this business is not for you and will not value out based on typical insurance agency metrics. With excellent reviews, this agency has managed to sell and secure over 1,700 policies and 3,700 customers with direct appointments (no aggregator) located in a southwest suburb of Cook County. Please also note there is a decent amount of non-standard policies within the book of business that is being sold, i.e. 25% standard / 75% non-standard. Carriers included, but are not limited to: Progressive, Nationwide, Berkshire Hathaway (Guard), Hartford, First Chicago, and Foremost. It comes with an excellent, affordable office space. Word of mouth has been their only source of growth so there is still tremendous room to grow with marketing. 2025 gross revenue was over $750k with $370k in SDE. Speaking Arabic would be an absolute plus, but not necessary based on the clientele and location of the agency. This an excellent tack on for a buyer that already has an agency and/or it can be rebranded as needed. The seller's preferences would be a buyer that already knows the insurance industry, but it can also serve as a massive head start for someone trying to break into the insurance industry. Inquire within for more information. PREFERRED CASH OR CONVENTIONAL LENDING BUYER FUNDING.

Cash Flow $373,630
Revenue $757,376

Asking Price: $350,000

African Fashion Store-Includes Seller Support

Chicago, IL
Cook County

For over 15 years, this Chicago-based African fashion boutique has been a beloved destination for vibrant, authentic African clothing, shoes, jewelry, bags, arts and crafts, and waist beads. The store specializes in offering a curated selection of high-quality items sourced from diverse countries, including Ghana, Dubai, Nigeria, Italy, and beyond, creating a unique fusion of global styles and traditional African craftsmanship.The business is known for its rich cultural offerings and has established strong relationships with international dealers, designers, and wholesalers, ensuring the authenticity and exclusivity of its inventory. Customers have long appreciated the boutique’s commitment to providing items that celebrate African heritage while embracing modern trends.As the current owner prepares to transition the business, they are committed to staying on as a consultant to help the new owner seamlessly continue the boutique’s legacy. This support will include guidance on importing the specialty items and transferring well-established relationships with international suppliers. The seller’s mentorship will ensure the new owner not only preserves but also enhances these crucial connections, enabling a smooth and successful transition.This is an excellent opportunity for a buyer passionate about fashion, culture, and global business, with the added benefit of ongoing support from a seasoned professional in the industry.

Cash Flow Not Disclosed
Revenue Not Disclosed

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